An image illustrating how Pro-Tumor Inflammation feeds the tumor

Pro-Tumor Inflammation (PTI) is one of the drivers of tumor survival, growth, and progression. IL-1β plays a key role in PTI.^1,2

Multiple other cell types and cytokines are also implicated in PTI, including other interleukins, TNF-α, and macrophages.³

PTI is one of the drivers of tumor growth and suppression of immune response³

Find out about PTI >

IL-1β plays a key role in PTI²

Learn about IL-1β >

TNF-α, tumor necrosis factor alpha.

References:
1. Chaudhry SI, Hooper S, Nye E, Williamson P, Harrington K, Sahai E. Oncogene. 2013;32(6):747-758.
2. Carmi Y, Doton S, Rider P, et al. J Immunol. 2013;190(7):3500-3509.
3. Grivennikov SI, Greten FR, Karin M. Cell. 2010;140(6):883-899.

This is a global website and is intended for health care professionals. The information on this site is intended for educational purposes only and is not country-specific.

Use of website is governed by the Terms of Use and Privacy Policy.

6/20 G-CAN-1232941

Pro-Tumor Inflammation (PTI) is one of the drivers of tumor survival, growth, and progression. IL-1β plays a key role in PTI.1,2

Multiple other cell types and cytokines are also implicated in PTI, including other interleukins, TNF-α, and macrophages.3

PTI is one of the drivers of tumor growth and suppression of immune response3

IL-1β plays a key role in PTI2

Finding New Ways Forward

Pro-Tumor Inflammation (PTI) is one of the drivers of tumor survival, growth, and progression. IL-1β plays a key role in PTI.^1,2

Multiple other cell types and cytokines are also implicated in PTI, including other interleukins, TNF-α, and macrophages.³

PTI is one of the drivers of tumor growth and suppression of immune response³

IL-1β plays a key role in PTI²