What is Pro-Tumor Inflammation and its role incancer?1
Early tumor growth and proliferation may be driven by Pro-Tumor Inflammation (PTI) and other factors.2 PTI is a type of unregulated inflammation that promotes tumor growth.3-6
1. Hanahan D. Cancer Discov. 2022;12(1):31-46. 2.Millares L, Barreiro E, Cortes R, et al. Lung Cancer. 2018;122:124-130. 3. Grivennikov SI, Greten FR, Karin M. Cell. 2010;140(6):883-889. 4. Greten FR, Grivennikov SI. Immunity. 2019;51(1):27-41. 5. Fleit HB. Pathobiology of Human Disease: A Dynamic Encyclopedia of Disease Mechanisms. 2014:300-314. 6. Lu H, Ouyang W, Huang C. Mol Cancer Res. 2006;4(4):221-233.