Pro-Tumor Inflammation is one of the drivers of tumor growth, survival, and progression in certain cancers1,2

Pro-Tumor Inflammation (PTI) refers to a type of unregulated inflammation that has many possible downstream consequences, such as facilitating tumor growth and metastasis in certain cancers.1,3,4 PTI can also create a tumor microenvironment that suppresses the immune response.1,3

Find out how PTI can impact cancer

View resources about PTI and cancer

Explore answers to Frequently Asked Questions about PTI

1. Grivennikov SI, Greten FR, Karin M. Cell. 2010;140(6):883-899.
2. Greten FR, Grivennikov SI. Immunity. 2019;51(1):27-41.
3. Fleit HB. Part I. In: Pathobiology of Human Disease: A Dynamic Encyclopedia of Disease Mechanisms. 2014:300-314.
4. Lu H, Ouyang W, Huang C. Mol Cancer Res. 2006;4(4):221-233.